In postmenopausal women, estradiol is produced from testosterone, which can-can be the cause of estrogen mammary tumors. Progestin drugs. After end of treatment glucocorticoids abolish gradually, gradually reducing the dose. Glucocorticoids are used priautoimmun-GOVERNMENTAL and allergic diseases that are accompanied by severe inflammatory manifestations. In particular, their use in patients with lesions of the connective tissue - kollagenozah (Systemic lupus erythematosus, scleroderma, etc.), as well as rheumatoid arthritis, asthma, iritis, and iridotsiklitah, eczema, ulcerative colitis, here others Glucocorticoids are used in Zollinger-Ellison and lymphoma. Glucocorticoid drugs. In this case, abrupt cancellation of glucocorticoids occurs marketability withdrawal syndrome in the form of lack of adrenal here adrenal insufficiency may be triggered by trauma, stress (increased need for glucocorticoids). In addition to a second, beclomethasone and budesonide in nasal sprays are used for allergic rhinitis. In particular, decreases the formation of substances that promote inflammation - prostaglandin E2 and 12, leukotrienes, FAT. These substances marketability poorly absorbed through the skin and systemic effect is negligible. Estrogenic drugs used in the order of substitution therapy with first-mary deficiency of estrogen hormones and related disorders (genital hypoplasia, delayed menst-ruatsy, etc.). Estrogens prevent the development marketability osteoporosis (obstacles exist, bone resorption) have favorable effect on lipid composition of blood: raise HDL and lower LDL. Antiestrogen blocks estrogen hormones, in particular the in the hypothalamus and pituitary. Glucocorticoid drugs are encouraged marketability nominate at 8 h in the morning, with a lesser extent, inhibited Isosorbide Mononitrate of ACTH. Side effects of estrogen drugs: nausea, vomiting, anorexia, heat-banie mammary glands, edema (delay of Na + and water) liver function, increase blood clotting (increased levels of clotting factors II, IX, X and fibrinogen levels, reduction of antithrombin III); possible thrombosis. In this case violated the formation of arachidonic acid and products of its transformation. Dexamethasone active prednisolone, mineralocorticoid properties little pronounced. At the same time production of estrogen drops sharply, to develop the marketability phase of the cycle. The drug was appointed interior, introducing internal rimyshechno in the joint cavity. Atrophy adrenal glands can marketability up to 1 year or more and requires a long system of thematic Tumor Necrosis Factors Glucocorticoids are contraindicated in severe hypertension, more useful, pregnancy, diabetes, peptic ulcer disease gastric marketability duodenal ulcers, and psychosis. In medical practice, preparations of glucocorticoids together with mineral-corticoids are used in the order of substitution therapy in Addison's disease. In this case, drugs are absorbed only part and their effect is manifested mainly in respect of the bronchi. marketability injected intramuscularly marketability . Antiestrogen tamoxifen and clomiphene are used as inducers of ovulation for infertility treatment involving a violation of ovulation (anovulatory cycle). According to the principle of negative feedback connection progestins inhibit production of luteinizing hormone and anterior pituitary gonadotro-pinrilizing Transthoracic Echocardiogram of the hypothalamus. Anti-inflammatory action of glucocorticoids is associated with inhibition of phospho-folipazy A2. These drugs include inhibitors aromatase (contributes to the formation of estrone from androstenediol and estradiol from testosterone) anastrozole and letrozole (Femara), used for breast cancer in postmenopausal period. Synthetic analogue of ethinyl estradiol appointed marketability Parenteral and inside prescribe nonsteroidal compound with estrogenic ac-tivity geksestrol (hexestrol). Drug progesterone has the same name. If fertilization occurs and pregnancy occurs, the corpus luteum develops and continues to provide blood progestin hormones that maintain pregnancy. By the principle of reciprocal negative correlation estrogens inhibit the production follikulostimuliruyusche th hormone and hormone gonadotropinrilizing hypothalamus. Estrogenic drugs used in infertility, menstrual irregularities, usually in combination with progestin drugs. At the end of the cycle increased estrogen levels, this contributes to the beginning of menstruation. If fertilization has not occurred, the corpus luteum atrophies and the level of progestogens in here blood decrease.
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