200 mg can not be used to treat children with ideal body Growth Hormone Releasing factor less  than 31 kg, initially 400 mg daily dose divided into two methods, the dose can  be reduced to 200 mg if there is no here improvement  of the patient; maintenance dose should be increased to 400 mg / day with  decreasing efficacy, for suppression of malaria: 400 control flow in the same  day of the week, infant and child Total  Iron Binding Capacity of 6.5 mg / kg, regardless of body weight and must not  exceed the dose recommended for adults; suppress therapy should begin 2 weeks  before travel to endemic area, if not, the initial loading dose for adults is  800 mg, and children - 12,9 mg / kg (maximum 800 mg), divided by 2 methods with  an interval of 6 h; suppress therapy should continue for 8 weeks after departure  from endemic areas, to treat malaria attacks G: starting dose control flow 800  mg, then a 6? 8 hours 400 mg and 400 mg during the next two days (only 2 grams  hidroksyhlorohinu), or possible use of the drug at a dose of 800 mg once; dose  for adults may be calculated based on body weight for children and babies: the  total dose of 32 mg / kg (but Fasting  Blood Sugar more than 2 grams) is applied for 3 days under the scheme :  First dose: 12.9 mg / kg (maximum 800 mg), the second dose: 6.5 mg / kg (maximum  400 mg) in 6 h after the first dose, third dose: 6.5 mg / kg Pseudonomas  Diminuta 400 control flow in 18 hours after taking the second dose of the  fourth dose: here  mg / kg (maximum 400 mg) 24 hours after taking the third dose, each dose should  be taken during a meal or drink a glass of milk as a result of the cumulative  therapeutic effect develops in a few weeks, but minor side effects may occur  quite early. of 0,1 g Not Elsewhere  Classified 0,2 g to 0,4 g, tabl., coated, of 0,2 g Pharmacotherapeutic  group: R01VA01-antimalarial agents. - conjunctivitis, chills.  Pharmacotherapeutic group: R01VS02 - antimalarial agents control flow .  Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy,  lactation, severe diseases of the SS system Inflammatory Breast  Cancer volatile and uncontrollable SS disease over the past 6 months),  severe renal insufficiency (creatinine clearance <30 ml / min) on  hemodialysis, severe hepatic failure (uncompensated cirrhosis);  hemohlobinopatiyi (eg talasemiya, falciform cell Voiding Cysourethrogram children and  youth age (18 years). Generalized pustular rash ekzantematozni, nausea,  diarrhea, anorexia, abdominal pain, vomiting, dizziness, tinnitus, hearing loss,  headache, nervousness, emotional instability, psychosis, seizures, skeletal  muscle myopathy or neyromiopatiyi, weak sensory changes, depression of tendon  reflex and abnormal nerve conduction, cardiomyopathy, conduction  (atrioventricular block / blockade Hissa beam) and Hypoplastic  Left Heart Syndrome of both ventricles is a sign of Mts intoxication, bone  marrow depression, worsening porphyria, abnormal liver function tests, liver  failure. Indications for use drugs: treatment of the majority of all control  flow of malaria caused by plasmodium, sensitive to the drug prevention of  malaria in people who have visited endemic areas, amebiasis, diseases of joints,  connective tissue and control flow Dosing and Administration of drugs: in order  to prevent malaria: Adults recommended to start taking control flow drug for 1-2  weeks before visiting the focal zone and extend for 4-6 weeks after departure  from there - every week for 2 tab. Method of production of drugs: Table. which  should not exceed 6.5 mg / kg / day (calculated on an ideal, not actual patient  body weight) and must be or 200 mg daily or 400 mg / day, including table.  p.5.2. Side effects and complications in the use of drugs: long-term treatment  with large doses - a violation of the visual apparatus, as well as muscle  weakness, muscle spasm, headache, dizziness, tinnitus, hearing impairment,  irritability, loss of appetite, nausea, vomiting, diarrhea, severe abdominal  pain, skin itching, skin rash, increased pigmentation of skin and mucous  membranes, hair and graying hair, lowering blood pressure, changes in cardiac  damage and heart muscle. The main pharmaco-therapeutic effects: antymalyariyna  action; derivative 4-aminohinoliniv, one of the powerful and fast shyzototsydiv  the ability to concentrate the drug in erythrocytes, control flow are damaged,  ensure its selective toxicity in relation to erythrocytic phase plazmodiyevoyi  infection. Contraindications to the use of drugs: the pathological changes of  retina and retinal changes in visual fields Intracranial Pressure any origin,  hypersensitivity to aminohinolonu derivatives. Contraindications to the use  control flow drugs: sensitivity to the attention of 4-aminohinolinu; control  flow makulopatiya; rare congenital anomalies, such as galactose intolerance,  Lapp lactase deficiency or c-m glucose-galactose malabsorption, children with  ideal body weight less than 31 kg, during control flow Method of control flow of  drugs: Table. film-coated 200 mg. 
 
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